Auraptene Size:Contact [email protected] for quotation thereby abrogating NF-κB binding and

thereby abrogating NF-κB binding and p300 recruitment to COX-2 promoter

Roflumilast-N-oxide also shows stronger glucose-lowering effects than its parent compound

compared with vehicle control and to mice undergoing daily treatment with JQ1 (50 mg/kg/day i

InChi: InChI=1S/C19H27N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4

It inhibits LSD1 with an IC50 ~5 nM

Auraptene Size:Contact [email protected] for quotation thereby abrogating NF-κB binding andAuraptene is the most abundant naturally occurring geranyloxycoumarin. Auraptene decreases the secretion of matrix metalloproteinase 2 (MMP 2) as well as key inflammatory mediators, including IL 6, IL 8, and chemokine (C C motif) ligand 5(CCL5). Product information CAS Number: 495 02 3 Molecular Weight: 298. 38 Formula: C19H22O3 Chemical Name: 7 {[(2E) 3,7 dimethylocta 2,6 dien 1 yl]oxy} 2H chromen 2 one Smiles: CC(C)=CCC C( C)=C