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3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 2174/1574887112666170406104854

SKU: 37206684933

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Description

2174/1574887112666170406104854

9b-trimethyl-7-(prop-1-en-2-yl)-1H

17)/t14-/m1/s1

457081-03-7

1-2H3/b13-3+/t14-

3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 2174/15748871126661704061048543 Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS like tyrosine kinase 3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9. 8 M in culture medium and plasma, respectively. 3 Hydroxy Midostaurin is less selective but more cytotoxic than PKC412. Product information CAS Number: 179237 49 1 Molecular Weight: 600. 66 Formula: C36H32N4O5 Chemical Name: N [(2R,4S,5S,7R) 17 hydroxy 5 methoxy 7 methyl 19 oxo

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