Iptacopan Size:Contact [email protected] for quotation Chemical Name: 6-amino-2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-amino-3-(4-hydroxyphenyl)propanamido]-3-hydroxybutanamido}-3-carboxypropanamido)-3-methylpentanamido]-4-carboxybutanamido}-4-(methylsulfanyl)butanamido)-3-carbamoylpropanamido]-5-[(diaminomethylidene)amino]pentanamido}-4-methylpentanamido)acetamido]hexanoic acid

Chemical Name: 6-amino-2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-amino-3-(4-hydroxyphenyl)propanamido]-3-hydroxybutanamido}-3-carboxypropanamido)-3-methylpentanamido]-4-carboxybutanamido}-4-(methylsulfanyl)butanamido)-3-carbamoylpropanamido]-5-[(diaminomethylidene)amino]pentanamido}-4-methylpentanamido)acetamido]hexanoic acid

GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model

0001) and day 22 (p<0

C6H8O7/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43

4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)methyl)phosphonate

Iptacopan Size:Contact [email protected] for quotation Chemical Name: 6-amino-2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-amino-3-(4-hydroxyphenyl)propanamido]-3-hydroxybutanamido}-3-carboxypropanamido)-3-methylpentanamido]-4-carboxybutanamido}-4-(methylsulfanyl)butanamido)-3-carbamoylpropanamido]-5-[(diaminomethylidene)amino]pentanamido}-4-methylpentanamido)acetamido]hexanoic acidIptacopan (LNP023) is a first in class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high affinity binding to human factor B with a KD of 7. 9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G). Product information CAS Number: 1644670 37 0 Molecular Weight: 422. 52 Formula: C25H30N2O4 Chemical Name: 4 [(2S,4S) 4 ethoxy 1 [(5