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InChi: InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3
Purvalanol A shows inhibitory activities against the NCI panel of 60 human tumor cell lines
and orally bioavailable inhibitors of the mammalian target of rapamycin kinase domain exhibiting single agent antiproliferative activity
Metacycline hydrochloride
9bR)-6-ethoxy-3a
Oprozomib iramate InChi: InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3Oprozomibm, also known as ONX 0912 and PR 047 , is a n orally bioavailable proteasome inhibitor with potential antineoplastic activity. ONX 0912 inhibits the activity of the proteasome, thereby blocking the targeted proteolysis normally performed by the proteasome; this may result in an accumulation of unwanted or misfolded proteins. Disruption of various cell signaling pathways may follow, eventually leading to the induction of apoptosis and
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