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LP-533401 Size:Contact [email protected] for quotation InChiKey: HQUPLSLYZHKKQT-WVVFQGGUSA-N

SKU: 35495835013

4.8
USD100.00 USD150.00

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Description

InChiKey: HQUPLSLYZHKKQT-WVVFQGGUSA-N

Formula: C13H17NaO2

DMH1 (4-[6-(4-Isopropoxyphenyl)pyrazolo [1

Formula: C22H38O5

InChi: InChI=1S/C23H33N3O8/c1-3-32-22(28)19(13-12-18-9-5-4-6-10-18)24-17(2)21(27)25-14-7-11-20(25)23(29)33-15-8-16-34-26(30)31/h4-6

LP-533401 Size:Contact [email protected] for quotation InChiKey: HQUPLSLYZHKKQT-WVVFQGGUSA-NLP 533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut. LP 533401 completely inhibits serotonin production in Tph1expressing cells (RBL2H3 cells) at a dose of 1 M. Oral administration once daily for up to 6 weeks of this small molecule prevents the development of and fully rescues, in a dose dependent manner, osteoporosis in ovariectomized rodents because of an isolated increase in bone formation.

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