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InChi: InChI=1S/C31H31N5O2S2
Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice
Chemical Name: 1-[5-(1-methyl-1H-pyrazol-4-yl)-2-oxo-7-azatricyclo[9
(2016) Nat Commun
2006 Dec 15
Cenerimod Catalog No.:M13534-2 InChi: InChI=1S/C31H31N5O2S2Cenerimod (ACT 334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC50 of 1 nM. Cenerimod shows more than 36fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC50s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous. Product information CAS Number: 1262414 04 9 Molecular Weight: 453. 53
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