is a potent pan-PKC inhibitor against for PKCα
13R)-10-hydroxy-12
and inhibits CaM kinase II only at 4000-fold higher concentrations
2009 Apr 23
thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes
Amino-PEG11-amine 777cl-2-IN-2 is a potent pan-PKC inhibitorAmino PEG11 amine, a PEG based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES) based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer. Product information CAS Number: 479200 82 3 Molecular Weight: 544. 68 Formula: C24H52N2O11 Chemical Name: 3,6,9,12,15,18,21,24,27,30,33 undecaoxapentatriacontane 1,35 diamine Smiles: