ZJ 43 60075 Formula: C25H30F3N3O2

Formula: C25H30F3N3O2

9 nM and 3nM

6-²H₈)piperazin-1-yl]propyl}-10H-phenothiazine

3 hours) has anti-inflammatory activity by attenuating the UVB-induced IL-6 synthesis in HaCaT cells

Smiles: CC1=CC(CC(O)=O)=CC=C1

ZJ 43 60075 Formula: C25H30F3N3O2IC50: 2. 4 nM ZJ 43 is a N acetylaspartylglutamate (NAAG) peptidase inhibitor. The peptide neurotransmitter N acetylaspartylglutamate (NAAG) is reported to act as an agonist at group II metabotropic glutamate receptors. NAAG is inactivated by extracellular peptidase activity leading to yielding glutamate and N acetylaspartate. In vitro: As a potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III) with Kivalues of 0. 8 and 23 nM