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13 μM for G9a
an effective prodrug of Timolol
Need ultrasonic and warming) H2O : < 0
Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis (−CH-11)
5-dimethyl-4
PROTAC BRD2/BRD4 degrader-1 in C 13 μM for G9aPROTAC BRD2 BRD4 degrader 1 (compound 15) is a potent and selective BET protein BRD4 and BRD2 degrader. PROTAC BRD2 BRD4 degrader 1 rapidly induces reversible, long lasting, and unexpectedly selective removal of BRD4 and BRD2 over BRD3. It effectively inhibits solid tumors with low cytotoxic effect. PROTAC BRD2 BRD4 degrader 1 is composed of the BET inhibitor, a linker, and the ligand thalidomide for cereblon (CRBN) cullin 4A. Product information
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