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914471-09-3
Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone
2-d]pyrimidin-2-yl)thio]-acetamide
fluorocyclopentenylcytosine
2006 Nov 15
CAL-101 - CAS# 870281-82-6 richlormethiazide 914471-09-3Idelalisib, also known as CAL 101, is a PI3K delta inhibitor with potential immunomodulating and antineoplastic activities. CAL 101 inhibits the production of the second messenger phosphatidylinositol 3,4,5 trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K delta is expressed primarily in hematopoietic lineages. The
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