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InChi: InChI=1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21
Nielsen EØ
Smiles: CC(C)N(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N)C1CC(C1)CCC1NC2=CC=C(C=C2N=1)C(C)(C)C
induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway
4]triazin-7-yl)-3
Cetirizine dihydrochloride thine HCl H2O InChi: InChI=1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21Cetirizine hydrochloride is a potent second generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen induced asthma. Cetirizine hydrochloride is a carboxylated metabolite of hydroxyzine that acts as a selective Histamine H1 receptor inverse agonist. Compared to its parent compound, it shows similar antihistaminic activity, but with greater H1 selectivity and less sedative effects.
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