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selective and ATP-competitive CSF1R (cFMS) and c-Kit inhibitor
CAS Number: 1675201-83-8
Earp HS 3rd
is a small-molecule proapoptotic agent with potential antineoplastic activity
selective and cell permeable BRPF1 bromodomain inhibitor with IC50 ~ 80 nM
APX-115 free base - CAS# 1270084-92-8 size:10mg solid selective and ATP-competitive CSF1R (cFMS)APX 115 free base, CAS No. 1270084 92 8, also known as EWHA 18278, is a potent, orally active pan NADPH oxidase (Nox) inhibitor. APX 115 protects development of diabetic nephropathy in podocyte specific NOX5 transgenic mice. APX 115 might be a promising therapeutic agent for the treatment of DN because of its pan NOX inhibitory activity, including its NOX5 inhibitory activity, and also owing to its anti inflammatory effect. Product information CAS
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