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Formula: C28H26N4O4S2
PND-1186 has an IC50 of ~100 nM in breast carcinoma cells
which interestingly preceeds changes in H3K4me2 levels
InChiKey: GTTBEUCJPZQMDZ-HVTBMTIBSA-N
Formula: C25H30ClI2NO3
PD-1/PD-L1-IN 3 ermine Formula: C28H26N4O4S2PD 1 PD L1 IN 3, a macrocyclic peptide, is a potent and selective inhibitor of the PD 1 PD L1 and CD80 PD L1 interactions extracted from patent WO2014151634A1, compound No. 1. PD 1 PD L1 IN 3 interferes with PD L1 binding to PD 1 and CD80 by binding to PD L1, with IC50s of 5. 60 nM and 7. 04 nM, respectively. PD 1 PD L1 IN 3 can be used for the research of various diseases, including cancer and infectious diseases. Product information CAS Number:
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