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PD-089828 (10 µM
Nicholas Kwiatkowski
Formula: C9H9BrN2O3
K562 cells) treatment inhibits MAPK/ERK/JNK downstream signaling and diminishes Jak2/Stat3/Akt expression
2-diphenyl-1-picrylhydrazyl (DPPH)
Selumetinib sulfate 1123 PD-089828 (10 µMSelumetinib (AZD6244) is selective, non ATP competitive oral MEK1 2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1 2 phosphorylation. Product information CAS Number: 943332 08 9 Molecular Weight: 555. 76 Formula: C17H17BrClFN4O7S Chemical Name: 5 [(4 bromo 2 chlorophenyl)amino] 4 fluoro N (2 hydroxyethoxy) 1 methyl 1H 1,3 benzodiazole 6 carboxamide; sulfuric acid Smiles:
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