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It inhibits phosphorylation of the mTORC1 substrates 4E-BP1 and S6K1 as well as the mTORC2 substrate AKT in diverse cancer models in vitro and in vivo
also known as Rimiducid
a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depression
is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity
wtRyR1-HEK 293 pretreated with KB-R7943 (10 μM
A 410099.1 amide-PEG4-amine - CAS# 2446474-10-6 0331 It inhibits phosphorylation of theA 410099. 1 amide PEG4 amine, CAS No. 2446474 10 6, IAP ligand with PEG linker and terminal amine for onward chemistry Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide PEG4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2446474 10 6 Molecular Weight: 817. 02 Formula:
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