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AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chinese hamster ovary (CHO) cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0
Chemical Name: N-[5-({4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}carbamoyl)-2-methylphenyl]-5-(thiophen-2-yl)pyridine-3-carboxamide
Formula: C17H21N7
The potent localized inhibition of sebaceous glands by RU 58841 demonstrates the excellent potential of this compound as a topical drug for the treatment of acne and other androgen-mediated disorders
which suggests that heart might be one of the main target tissues of Columbianadin
Kaurenoic acid (Acetonide) AM095 is a potent LPA1Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NOcyclic GMPPKGATP sensitive potassium channel signaling pathway. Product information CAS Number: 6730 83 2 Molecular Weight: 302. 45 Formula: C20H30O2 Chemical Name: (1S,4S,5R,9S,10R,13R) 4,10 dihydrogenio 5,9 dimethyl 14 methylidenetetracyclo[11. 2. 1. 0,. 0,]hexadecane 5 carboxylic acid Smiles:
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