Famitinib Size:Contact [email protected] for quotation CAS Number: 1361224-53-4

CAS Number: 1361224-53-4

InChiKey: SZRPDCCEHVWOJX-UHFFFAOYSA-N

Formula: C48H54Cl2N10O2S2

CE3F4 (40 μM) specifically inhibits Epac1 guanine nucleotide exchange activity without interference with Rap1 activity or Epac1-Rap1 interaction

3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7

Famitinib Size:Contact [email protected] for quotation CAS Number: 1361224-53-4Famitinib (SHR1020), an orally active multi targeted kinase inhibitor, inhibits the activity of c kit, VEGFR 2 and PDGFR with IC50 values of 2. 3 nM, 4. 7 nM and 6. 6 nM, respectively. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis. Famitinib is a novel multi targeted receptor tyrosine kinase inhibitor under development for cancer treatment. Famitinib is a structural analogue of