Thalidomide 5-fluoride Catalog No.:M11562-10 Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@H](OC(=O)/C=C/C3=CC(O)=C(O)C=C3)[C@@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O[C@@H](OCCC3C=CC(O)=C(O)C=3)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@H](OC(=O)/C=C/C3=CC(O)=C(O)C=C3)[C@@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O[C@@H](OCCC3C=CC(O)=C(O)C=3)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

BMS-512148 (2S)-1

but was found to be ineffective

2-bis(4-fluorophenyl)-2-phenylacetamide

10(7):e0132004

Thalidomide 5-fluoride Catalog No.:M11562-10 Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@H](OC(=O)/C=C/C3=CC(O)=C(O)C=C3)[C@@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O[C@@H](OCCC3C=CC(O)=C(O)C=3)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1OThalidomide 5 fluoride is Thalidomide based cereblon ligand that incorporates to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader 1. Product information CAS Number: 835616 61 0 Molecular Weight: 276. 22 Formula: C13H9FN2O4 Chemical Name: 2 (2, 6 dioxopiperidin 3 yl) 5 fluoro 2, 3 dihydro 1H isoindole 1, 3 dione Smiles: O=C1CCC(C(=O)N1)N1C(=O)C2=CC(F)=CC=C2C1=O InChiKey: MPQLCQKBYRSPNA UHFFFAOYSA N InChi: InChI=1S C13H9FN2O4 c14 6