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at 6x10-8 M
The COX-2 inhibitor SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model
CDK6/cyclin D1
3Z)-3-(hydroxyimino)-2'-oxo-1'
Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux
Belinostat (PXD101) Catalog No.:M22445-C at 6x10-8 MBelinostat (also known as PXD101) is a novel and potent hydroxamate type inhibitor of histone deacetylase (HDAC) that inhibits the activity of HDAC in Hela cell extracts with 50% inhibition concentration IC50 value of 27 nM. Belinostat has been found to significantly increase the acetylation of histones H3 and H4 and exerts cytotoxicity in a wide range of tumor cell lines. In the treatment of urothelial carcinoma cell lines, belinostat dose