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Magaret CA
colon weight per unit length in the control group is more than twice that in the normal group
suggesting its selectivity towards cancer cells
Treatment of A549 cells with SW033291 increased PGE2 levels by 3
Chemical Name: 1H-Pyrrole-1-acetic acid
CL-387785 - CAS# 194423-06-8 Catalog No.:M7079-10 Magaret CACL 387785, CAS No. 194423 06 8, also known as EKI 785 , is a n irreversible inhibitor of EGF receptor (EGFR) kinase activity in vivo (IC50 = 250 490 pM). CL 387785 covalently bound to EGF R. It also specifically inhibited kinase activity of the protein (IC50 = 370+ 120 pM), blocked EGF stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31 125 nM) primarily in a cytostatic manner in
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