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InChi: InChI=1S/C28H30N6OS
a second generation bisphosphonate and synthetic analog of pyrophosphate with bone anti-resorption activity
477(7365):477-81
Siramesine involves lysosomal leakage and oxidative stress
46)47)40(53-43)66-32-7-2-4-24-9-12-31(55)36(24)32)38(58)48-15-17-64-19-21-65-20-18-63-16-14-35(57)50-29-6-3-5-26-37(29)42(61)54(41(26)60)30-11-13-34(56)52-39(30)59/h2-8
Lazertinib Catalog No.:M13413-2 InChi: InChI=1S/C28H30N6OSLazertinib (YH25448,GNS 1480) is a potent, highly mutant selective and irreversible EGFR TKI with IC50 values of 1. 7 nM, 2 nM, 5 nM, 20. 6 nM and 76 nM for Del19 T790M, L858R T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4. Product information CAS Number: 1903008 80 9 Molecular Weight: 554. 64 Formula: C30H34N8O3 Chemical Name: N {5 [(4 {4 [(dimethylamino)methyl] 3 phenyl 1H pyrazol 1
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