TAK-715 odiamide hydrate is a drug used for

is a drug used for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure

CAS Number: 68099-86-5

CAS Number: 131875-08-6

MLN-9708 treatment increases the levels of pro-apoptotic proteins and down regulates the anti-apoptotic proteins that control MOMP

InChiKey: HHHKFGXWKKUNCY-FHWLQOOXSA-N

TAK-715 odiamide hydrate is a drug used forTAK 715 is a potent p38 MAPK inhibitor. which displays potent inhibitory activity (inhibition of p38alpha, IC50 = 7. 1 nM; LPS stimulated release of TNF alpha from THP 1, IC50 = 48 nM; LPS induced TNF alpha production in mice, 87. 6% inhibition at 10 mg kg, po) and no inhibitory activity for major CYPs, including CYP3A4. TAK 715 was selected as a clinical candidate and is now under clinical investigation for the treatment of RA. Product information