A-192621 - CAS# 195529-54-5 0228 3)17-11-15(16-6-8-19-20(12-16)28-14-27-19)5-7-18(17)26-10-9-23(4)13-21(24)25

3)17-11-15(16-6-8-19-20(12-16)28-14-27-19)5-7-18(17)26-10-9-23(4)13-21(24)25

3)51(66)15-14-16-52-58(4

26097-80-3

in which the two hydroxy groups of GLYCEROL are esterified with fatty acids

thereby selectively and irreversibly blocking glucose uptake

A-192621 - CAS# 195529-54-5 0228 3)17-11-15(16-6-8-19-20(12-16)28-14-27-19)5-7-18(17)26-10-9-23(4)13-21(24)25A 192621 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4. 5 nM and a Ki of 8. 8 nM. The selectivity of A 192621 is 636 fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM). A 192621 promotes apoptosis in PASMCs. A 192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET 1 level. Product information CAS Number: 195529 54 5 Molecular Weight: 558. 66