GNE-6468 Catalog No.:M21940-C Smiles: C[C@]12CC[C@H](O)C[C@@H]1C(=O)C[C@@H]1[C@@H]2CC2[C@H]1CC[C@]1(O[C@@H]3C[C@H](C)CN[C@H]3[C@H]1C)C=2C

Smiles: C[C@]12CC[C@H](O)C[C@@H]1C(=O)C[C@@H]1[C@@H]2CC2[C@H]1CC[C@]1(O[C@@H]3C[C@H](C)CN[C@H]3[C@H]1C)C=2C

and p21 protein levels

Smiles: N[C@H]1CONC1=O

CAS Number: 257879-35-9

3)14-15-41(25

GNE-6468 Catalog No.:M21940-C Smiles: C[C@]12CC[C@H](O)C[C@@H]1C(=O)C[C@@H]1[C@@H]2CC2[C@H]1CC[C@]1(O[C@@H]3C[C@H](C)CN[C@H]3[C@H]1C)C=2CGNE 6468 is a highly potent and selective ROR (RORc) inverse agonist with an EC50 value of 13 nM for HEK 293 cell. GNE 6468 exhibits an EC50 of 30 nM for IL 17 PBMC. Product information CAS Number: 1677668 27 7 Molecular Weight: 433. 84 Formula: C23H16ClN3O4 Chemical Name: 4 [6 (2 chloro 6 cyclopropylbenzoyl)imidazo[1,5 a]pyrimidin 8 yl] 2 hydroxybenzoic acid Smiles: OC(=O)C1=CC=C(C=C1O)C1N=C(C(=O)C2C(Cl)=CC=CC=2C2CC2)N2C=CC=NC2=1 InChiKey: