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BI 653048 phosphate asaponin II Smiles: CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)C[C@@H](O)C/1=C

SKU: 21647303302

4.3
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Description

Smiles: CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)C[C@@H](O)C/1=C

Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-drug-conjugation (ADC)

Oseltamivir phosphate (OP) is a prodrug that is readily absorbed from the gastrointestinal tract after oral administration and is extensively converted predominantly by hepatic esterases to Oseltamivir carboxylate (OC)

for more than 26 days) significantly inhibits tumor growth in Raji tumor-bearing mice

Smiles: [O-][N+](=O)C1C=CC(=CC=1)OC1=CC(=CC(=C1)OC1C=CC(=CC=1)[N+]([O-])=O)C(O)=O

BI 653048 phosphate asaponin II Smiles: CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)C[C@@H](O)C/1=CBI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms activity and reduces affinity for the hERG ion channel (IC50>30 M). BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.

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