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3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51)
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Parasrampuria DA
2019 Nov 5
Formula: C23H21FO3
NI-42 amineα α β β-d4 dihydrochloride 3 μM for Candida albicansNI 42 (compound 13 d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1 2 3=7. 9 48 260 nM; Kds of BRPF1 2 3=40 210 940 nM) with excellent selectivity over nonclass IV BRD proteins. Product information CAS Number: 1884640 99 6 Molecular Weight: 353. 40 Formula: C18H15N3O3S Chemical Name: 4 cyano N (1,3 dimethyl 2 oxo 1,2 dihydroquinolin 6 yl)benzene 1 sulfonamide Smiles:
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